Tourniquet-induced neuromuscular injury
نویسندگان
چکیده
منابع مشابه
Tourniquet-induced hypertension.
The anaesthetic records of 600 patients undergoing lower limb surgery were reviewed to determine the frequency of intraoperative arterial hypertension (defined as a 30% incision). The overall frequency of hypertension during operation in 500 patients to whom a tourniquet was applied during surgery was 11%. The probability of hypertension was increased if the patient was elderly, had cardiac enl...
متن کاملMorphological Regeneration and Functional Recovery of Neuromuscular Junctions after Tourniquet-Induced Injuries in Mouse Hindlimb
Tourniquet application and its subsequent release cause serious injuries to the skeletal muscle, nerve, and neuromuscular junction (NMJ) due to mechanical compression and ischemia-reperfusion (IR). Monitoring structural and functional repair of the NMJ, nerve, and skeletal muscle after tourniquet-induced injuries is beneficial in exploring potential cellular and molecular mechanisms responsible...
متن کاملProtective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb
BACKGROUND Studies have shown that ischemia-reperfusion (I/R) produces free radicals leading to lipid peroxidation and damage to skeletal muscle. The purposes of this study were 1) to assess the histological findings of gastrocnemius muscle (GC) and tibialis anterior muscle (TA) in I/R injury model mice, 2) to histologically analyze whether a single pretreatment of edaravone inhibits I/R injury...
متن کاملThe effect of recombinant human MG53 protein on tourniquet- induced ischemia reperfusion injury in rat muscle
Introduction—Skeletal muscle ischemia reperfusion injury (I-R) is a complex injury process that includes damage to the sarcolemmal membrane, contributing to necrosis and apoptosis. MG53, a muscle-specific TRIM family protein, has been shown to be essential for regulating membrane repair and has been shown to be protective against cardiac I-R and various forms of skeletal muscle injury. The purp...
متن کاملInfluence of fiber-type composition on recovery from tourniquet-induced skeletal muscle ischemia-reperfusion injury.
This study was designed to determine if previously reported differences in the functional impairment of muscles composed of predominantly different fiber types occurs following extended periods of ischemia. We hypothesized that the soleus (Sol) muscle, a predominantly slow-twitch muscle, would be less vulnerable to tourniquet-induced ischemia-reperfusion than the plantaris (Plant), a predominan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Orthopaedica Scandinavica
سال: 1991
ISSN: 0001-6470
DOI: 10.3109/17453679109153924